After surgery to remove the tumor, the uninflated GliaSite balloon catheter is placed inside the space left by the removal of the malignant brain tumor. The other end of the catheter extends outside of the skull and is concealed underneath the skin at the top of the head.

Once the patient has recovered from surgery (as soon as three days later), Iotrex^® Radiotherapy Solution, a liquid radiation source, and saline are injected into the catheter to fill the balloon. Iotrex Radiotherapy Solution delivers radiation to the edges of the tumor cavity, targeting places where cancer may remain.

The Iotrex Radiotherapy Solution and saline mixture stay in the balloon catheter for approximately 3 to 7 days, until the right amount of radiation is delivered. Patients typically experience little to no discomfort during radiation treatment. Most patients read books, watch TV, and carry out their activities of daily living while in the hospital or in an outpatient setting.

The Iotrex Radiotherapy Solution and saline mixture is then withdrawn and the GliaSite catheter is removed during a brief surgical procedure.